Natural Killer Cell Responses during Human ?-Herpesvirus Infections
نویسندگان
چکیده
Herpesviruses are main sculptors of natural killer (NK) cell repertoires. While the ?-herpesvirus human cytomegalovirus (CMV) drives accumulation adaptive NKG2C-positive NK cells, ?-herpesvirus Epstein–Barr virus (EBV) expands early differentiated NKG2A-positive cells. cells support immunity by antibody-dependent cellular cytotoxicity, seem to preferentially target lytic EBV replicating B The importance this restriction replication during pathogenesis will be discussed. Furthermore, modification EBV-driven expansion coinfections, including other Kaposi sarcoma-associated herpesvirus (KSHV), summarized.
منابع مشابه
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ژورنال
عنوان ژورنال: Vaccines
سال: 2021
ISSN: ['2076-393X']
DOI: https://doi.org/10.3390/vaccines9060655